Spotlight: Systemic lupus erythematosus (SLE/Lupus) Systemic lupus erythematosus (SLE), also commonly called lupus, is a chronic, systemic, autoimmune inflammatory condition, mainly affecting connective tissue. Lupus impacts multiple organ systems including the skin, muscles, joints, lungs, kidneys, central nervous system and blood. The hallmarks of lupus are the production of large numbers of autoantibodies and circulating immune complexes that are deposited in various tissues and organs around the body. Key Symptoms Because lupus is a multi-system disease, individuals can present with…